Expression of fascin protein and mRNA in the KB carcinoma cell line following treatment with doxorubicin
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منابع مشابه
Immunohistochemical Evaluation of Fascin in Oral Squamous Cell Carcinoma
Background and purpose: Squamous cell carcinoma (SCC) is the eighth most common cancer in men and the fifteenth in women. Localized recurrence and metastasis to regional lymph nodes are major problems in these patients. Fascin is a 55- kDa protein from the family of actin-binding proteins that is expressed in cells with membranous bronchial tubes. The aim of this study was to evaluate the expre...
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Background: Rad51 is a protein with critical role in double strand break repair. Down-regulation of this protein has a significant effect in radiosensitivity of some cell lines like prostate carcinoma. Compared to monolayer cell culture model, the spheroids are more resistant to radiation. The aim of the current study was to determine the Rad51 protein level in DU145 spheroids, and monol...
متن کاملFascin Expression in Oral Squamous Cell Carcinoma using an Immunohistochemical Technique
Introdouction: Oral squamous cell carcinoma (OSCC), the most common form of oral cancer, requires early diagnosis and suitable treatments. Fascin is a protein involved in cell adhesion and is increased in expression in certain types of carcinomas. The present study was conducted to assess fascin expression in OSCC using an immunohistochemical technique. Materials and methods: In the present re...
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Evaluating the Toxicity of Doxorubicin-Silk Fibroin Nanoparticles and Its Effect on P53 Gene Expression in Breast Cancer Cell Line
Introduction: The use of drug delivery systems can increase the effectiveness of chemotherapy and reduce its side effects in the treatment of breast cancer. This study aimed to evaluate the effect of doxorubicin-containing silk fibroin nanoparticles (NF-DOX) on P53 gene expression in breast cancer cell lines and to measure its toxicity in vitro. Methods: NF-DOX was synthesized and characterize...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2011
ISSN: 0973-1482
DOI: 10.4103/0973-1482.92009